Safety evaluation of a natural eggshell membrane-derived product
نویسندگان
چکیده
منابع مشابه
Natural product and natural product derived drugs in clinical trials.
There are a significant number of natural product (NP) drugs in development. We review the 100 NP and NP-derived compounds and 33 Antibody Drug Conjugates (ADCs) with a NP-derived cytotoxic component being evaluated in clinical trials or in registration at the end of 2013. 38 of these compounds and 33 ADCs are being investigated as potential oncology treatments, 26 as anti-infectives, 19 for th...
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Alzheimer's disease is characterized by pathogenic oligomerization, aggregation, and deposition of amyloid beta peptide (Aβ), resulting in severe neuronal toxicity and associated cognitive dysfunction. In particular, increases in the absolute or relative level of the major long form of Aβ, Aβ42, are associated with increased cellular toxicity and rapidity of disease progression. As a result of ...
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References 1. Koch MA, Wittenberg LO, Basu S, Jeyaraj DA, Gourzoulidou E, Reinecke K, Odermatt A, Waldmann H: PNAS 2004, 101:16721-16726. 2. Koch MA, Schuffenhauer A, Scheck M, Wetzel S, Casaulta M, Odermatt A, Ertl P, Waldmann H: Charting biologically relevant chemical space: A structural classification of natural products (SCONP). PNAS 2005, 102:17272-17277. 3. Schuffenhauer A, Ertl P, Roggo ...
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ژورنال
عنوان ژورنال: Food and Chemical Toxicology
سال: 2012
ISSN: 0278-6915
DOI: 10.1016/j.fct.2011.12.036